MOLECULAR & CELLULAR PATHOLOGY – Dottorato di Ricerca in Medicina Sperimentale DMS

Most recent publications

Valenti GE, Roveri A, Venerando R, Menichini P, Monti P, Tasso B, Traverso N, Domenicotti C, Marengo B.
PTC596-Induced BMI-1 Inhibition Fights Neuroblastoma Multidrug Resistance by Inducing Ferroptosis.
Antioxidants (Basel). 2024;13(1):3. doi: 10.3390/antiox13010003.

Schepers M, Hendrix S, Mussen F, van Breedam E, Ponsaerts P, Lemmens S, Hellings N, Ricciarelli R, Fedele E, Bruno O, Brullo C, Prickaerts J, Van Broeckhoven J, Vanmierlo T.

Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition.

Neurotherapeutics. 2024 May 16;21(4):e00372. doi: 10.1016/j.neurot.2024.e00372.

Bertoncini-Silva C, Vlad A, Ricciarelli R, Giacomo Fassini P, Suen VMM, Zingg JM.
Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment.
Antioxidants (Basel). 2024 Mar 8;13(3):331. doi: 10.3390/antiox13030331.

Barisione C, Verzola D, Garibaldi S, Altieri P, Furfaro AL, Nitti M, Pratesi G, Palombo D, Ameri P.

Indoxyl sulphate-initiated activation of cardiac fibroblasts is modulated by aryl hydrocarbon receptor and nuclear factor-erythroid-2-related factor 2.
J Cell Mol Med. 2024 Apr;28(7):e18192. doi: 10.1111/jcmm.18192.

Cassottana P, Iester C, Bonzano L, Traverso CE, Iester M.
Quantitative evaluation of OCT angiography images in healthy and glaucomatous subjects through a novel approach: exploring inter-image variability.
Eye (Lond). 2024 Jul;38(10):1903-1907. doi: 10.1038/s41433-024-03038-9.

Sirito T, Cassottana P, Iester M, Laroni A.
Central serous chorioretinopathy in multiple sclerosis and its differential diagnosis with optic neuritis: a case report.
Neurol Sci. 2024 May 8. doi: 10.1007/s10072-024-07544-2.

Garbarino O, Valenti GE, Monteleone L, Pietra G, Mingari MC, Benzi A, Bruzzone S, Ravera S, Leardi R, Farinini E, Vernazza S, Grottoli M, Marengo B, Domenicotti C.
PLX4032 resistance of patient-derived melanoma cells: crucial role of oxidative metabolism.
Front Oncol. 2023 Jul 18;13:1210130. doi: 10.3389/fonc.2023.1210130.

Tirendi S, Marengo B, Domenicotti C, Bassi AM, Almonti V, Vernazza S.
Colorectal cancer and therapy response: a focus on the main mechanisms involved.
Front Oncol. 2023 Jul 19;13:1208140. doi: 10.3389/fonc.2023.1208140.

Alfei S, Milanese M, Brullo C, Valenti GE, Domenicotti C, Russo E, Marengo B.
Antiproliferative Imidazo-Pyrazole-Based Hydrogel: A Promising Approach for the Development of New Treatments for PLX-Resistant Melanoma.
Pharmaceutics. 2023 Oct 4;15(10):2425. doi: 10.3390/pharmaceutics15102425.

Valenti GE, Marengo B, Milanese M, Zuccari G, Brullo C, Domenicotti C, Alfei S.
Imidazo-Pyrazole-Loaded Palmitic Acid and Polystyrene-Based Nanoparticles: Synthesis, Characterization and Antiproliferative Activity on Chemo-Resistant Human Neuroblastoma Cells.
Int J Mol Sci. 2023 Oct 9;24(19):15027. doi: 10.3390/ijms241915027.

Ivaldo C, Passalacqua M, Furfaro AL, d’Abramo C, Ruiz S, Chatterjee PK, Metz CN, Nitti M, Marambaud P.
Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10.
Sci Rep. 2023 Jan 11;13(1):597. doi: 10.1038/s41598-022-27308-2.

Cutolo CA, Bonzano C, Catti C, Pizzorno C, Bagnis A, Traverso CE, Iester M.
Reoperations for complications within 90 days after gel stent implantation or trabeculectomy.
Int Ophthalmol. 2023 May;43(5):1745-1749. doi: 10.1007/s10792-022-02575-0.

Cassottana P, Toma C, Maltese C, Villa V, Ricciarelli R, Traverso CE, Iester M.
A Case of Bilateral Choroidal Effusion after XEN Gel Stent Implantation.
Gels. 2023 Mar 27;9(4):276. doi: 10.3390/gels9040276.

Montalto G, Ricciarelli R.
Tau, tau kinases, and tauopathies: An updated overview.
Biofactors. 2023 May-Jun;49(3):502-511. doi: 10.1002/biof.1930.

Paes D, Schepers M, Willems E, Rombaut B, Tiane A, Solomina Y, Tibbo A, Blair C, Kyurkchieva E, Baillie GS, Ricciarelli R, Brullo C, Fedele E, Bruno O, van den Hove D, Vanmierlo T, Prickaerts J.
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology.
Cell Mol Life Sci. 2023 Jun 12;80(7):178. doi: 10.1007/s00018-023-04804-w.

Avitabile M, Bonfiglio F, Aievola V, Cantalupo S, Maiorino T, Lasorsa VA, Domenicotti C, Marengo B, Zbyněk H, Vojtěch A, Iolascon A, Capasso M.
Single-cell transcriptomics of neuroblastoma identifies chemoresistance-associated genes and pathways.
Comput Struct Biotechnol J. 2022 Aug 18;20:4437-4445. doi: 10.1016/j.csbj.2022.08.031.

Domenicotti C, Marengo B.
Paradox Role of Oxidative Stress in Cancer: State of the Art.
Antioxidants (Basel). 2022 May 23;11(5):1027. doi: 10.3390/antiox11051027.

Monteleone L, Marengo B, Musumeci F, Grossi G, Carbone A, Valenti GE, Domenicotti C, Schenone S.
Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells.
Pharmaceutics. 2022 Jul 1;14(7):1399. doi: 10.3390/pharmaceutics14071399.

Valenti GE, Alfei S, Caviglia D, Domenicotti C, Marengo B.
Antimicrobial Peptides and Cationic Nanoparticles: A Broad-Spectrum Weapon to Fight Multi-Drug Resistance Not Only in Bacteria.
Int J Mol Sci. 2022 May 29;23(11):6108. doi: 10.3390/ijms23116108.

Furfaro AL, Loi G, Ivaldo C, Passalacqua M, Pietra G, Mann GE, Nitti M.
HO-1 Limits the Efficacy of Vemurafenib/PLX4032 in BRAF^V600E Mutated Melanoma Cells Adapted to Physiological Normoxia or Hypoxia.
Antioxidants (Basel). 2022 Jun 14;11(6):1171. doi: 10.3390/antiox11061171.

Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C, Traverso N.
Hormesis and Oxidative Distress: Pathophysiology of Reactive Oxygen Species and the Open Question of Antioxidant Modulation and Supplementation.
Antioxidants (Basel). 2022 Aug 19;11(8):1613. doi: 10.3390/antiox11081613.

Sindaco D, Cappelli F, Vagge A, Traverso CE, Iester M.
Ophthalmologic evaluation in vitamin-E deficiency: A case report.
Eur J Ophthalmol. 2022 Jan;32(1):NP254-NP257. doi: 10.1177/1120672120970112.

Cassottana P, Di Mola I, Ferro Desideri L, Vagge A, Cutolo CA, Traverso CE, Iester M.
Blood Reflux Through a PreserFlo MicroShunt Device After Needling.
J Glaucoma. 2022 Dec 1;31(12):979-981. doi: 10.1097/IJG.0000000000002091.

Burlando B, Losacco S, Villa V, Fedele E, Ricciarelli R.
A New Bistable Switch Model of Alzheimer’s Disease Pathogenesis.
Int J Mol Sci. 2022 Jun 25;23(13):7061. doi: 10.3390/ijms23137061.

Villa V, Montalto G, Caudano F, Fedele E, Ricciarelli R.
Selective inhibition of phosphodiesterase 4D increases tau phosphorylation at Ser214 residue.
Biofactors. 2022 Sep;48(5):1111-1117. doi: 10.1002/biof.1847.