Most recent publications
Scarano N, Brullo C, Musumeci F, Millo E, Bruzzone S, Schenone S, Cichero E.
Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective.
Pharmaceuticals (Basel). 2024 May 8;17(5):601. doi: 10.3390/ph17050601.
Benzi A, Heine M, Spinelli S, Salis A, Worthmann A, Diercks B, Astigiano C, Pérez Mato R, Memushaj A, Sturla L, Vellone V, Damonte G, Jaeckstein MY, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Heeren J, Bruzzone S.
The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice.
Front Endocrinol (Lausanne). 2024 Feb 6;14:1251351. doi: 10.3389/fendo.2023.1251351.
Conforti I, Benzi A, Caffa I, Bruzzone S, Nencioni A, Marra A.
New Analogues of the Nicotinamide Phosphoribosyltransferase Inhibitor FK866 as Potential Anti-Pancreatic Cancer Agents.
Med Chem. 2024; 20:694. doi: 10.2174/0115734064289584240121142405.
Guarneri I, Bozzo M, Perez Criado N, Serafini E, Manfè G, Tagliapietra D, Fiorin R, Scapin L, Povero P, Bellitto D, Ferrando S, Amaroli A, Castellano L, Pestarino M, Schubert M, Candiani S.
Amphioxus (Branchiostoma lanceolatum) in the North Adriatic Sea: ecological observations and spawning behavior.
Integr Zool. 2024 Jun 17. doi: 10.1111/1749-4877.12846. Online ahead of print.
Spinelli S, Bruschi M, Passalacqua M, Guida L, Magnone M, Sturla L, Zocchi E.
Estrogen-Related Receptor α: A Key Transcription Factor in the Regulation of Energy Metabolism at an Organismic Level and a Target of the ABA/LANCL Hormone Receptor System.
Int J Mol Sci. 2024 Apr 27;25(9):4796. doi: 10.3390/ijms25094796.
Traverso F, Aicardi S, Bozzo M, Zinni M, Amaroli A, Galli L, Candiani S, Vanin S, Ferrando S.
New Insights into Geometric Morphometry Applied to Fish Scales for Species Identification.
Animals (Basel). 2024 Apr 3;14(7):1090. doi: 10.3390/ani14071090.
Spinelli S, Kajana X, Garbarino A, Bartolucci M, Petretto A, Pavanello M, Verrina E, Candiano G, Panfoli I, Bruschi M.
Proteomic Profiling of Cerebrospinal Fluid and Its Extracellular Vesicles from Extraventricular Drainage in Pediatric Pilocytic Astrocytoma, towards Precision Oncology.
Cancers (Basel). 2024 Mar 20;16(6):1223. doi: 10.3390/cancers16061223.
Vagaggini C, Petroni D, D’Agostino I, Poggialini F, Cavallini C, Cianciusi A, Salis A, D’Antona L, Francesconi V, Manetti F, Damonte G, Musumeci F, Menichetti L, Dreassi E, Carbone A, Schenone S.
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment.
Drug Dev Res. 2024 Feb;85(1):e22158. doi: 10.1002/ddr.22158.
Spallarossa A, Pedemonte N, Pesce E, Millo E, Cichero E, Rosano C, Lusardi M, Iervasi E, Ponassi M.
Cyclic diacyl thioureas enhance activity of corrector Lumacaftor on F508del-CFTR.
ChemMedChem. 2024 Feb 16;19(4):e202300391. doi: 10.1002/cmdc.202300391.
Zbeeb H, Khalifeh H, Lupidi G, Baldini F, Zeaiter L, Khalil M, Salis A, Damonte G, Vergani L.
Polyphenol-enriched extracts of Sarcopoterium spinosum fruits for counteracting lipid accumulation and oxidative stress in an in vitro model of hepatic steatosis.
Fitoterapia. 2024 Jan;172:105743. doi: 10.1016/j.fitote.2023.105743. Epub 2023 Nov 10.
Casazza AA, Capraro M, Pedrazzi M, D’Agostino G, Onofri F, Marte A, De Tullio R, Perego P, Averna M.
Temperature-Dependent Olive Pomace Extraction for Obtaining Bioactive Compounds Preventing the Death of Murine Cortical Neurons.
Int J Mol Sci. 2024 Jan 11;25(2):907. doi: 10.3390/ijms25020907.
Kajana X, Spinelli S, Garbarino A, Balagura G, Bartolucci M, Petretto A, Pavanello M, Candiano G, Panfoli I, Bruschi M.
Identification of Central Nervous System Oncologic Disease Biomarkers in EVs from Cerebrospinal Fluid (CSF) of Pediatric Patients: A Pilot Neuro-Proteomic Study.
Biomolecules. 2023 Nov 30;13(12):1730. doi: 10.3390/biom13121730.
Bruschi M, Candiano G, Angeletti A, Lugani F, Panfoli I.
Extracellular Vesicles as Source of Biomarkers in Glomerulonephritis.
Int J Mol Sci. 2023 Sep 9;24(18):13894. doi: 10.3390/ijms241813894.
Abbotto E, Miro C, Piacente F, Salis A, Murolo M, Nappi A, Millo E, Russo E, Cichero E, Sturla L, Del Rio A, De Flora A, Nencioni A, Dentice M, Bruzzone S.
SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma.
Biomed Pharmacother. 2023 Oct;166:115326. doi: 10.1016/j.biopha.2023.115326.
Benzi A, Heine M, Spinelli S, Salis A, Worthmann A, Diercks B, Astigiano C, Pérez Mato R, Memushaj A, Sturla L, Vellone V, Damonte G, Jaeckstein MY, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Heeren J, Bruzzone S.
The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice.
Front Endocrinol (Lausanne). 2023 Feb 6;14:1251351. doi: 10.3389/fendo.2023.1251351.
Bozzo M, Bellitto D, Amaroli A, Ferrando S, Schubert M, Candiani S.
Retinoic Acid and POU Genes in Developing Amphioxus: A Focus on Neural Development.
Cells. 2023 Feb 14;12(4):614. doi: 10.3390/cells12040614.
Mercurio S, Bozzo M, Pennati A, Candiani S, Pennati R.
Serotonin Receptors and Their Involvement in Melanization of Sensory Cells in Ciona intestinalis.
Cells. 2023 Apr 13;12(8):1150. doi: 10.3390/cells12081150.
Mirata S, Asnaghi V, Chiantore M, Salis A, Benvenuti M, Damonte G, Scarfì S.
Photoprotective and Anti-Aging Properties of the Apical Frond Extracts from the Mediterranean Seaweed Ericaria amentacea.
Mar Drugs. 2023 May 18;21(5):306. doi: 10.3390/md21050306.
Vivado D, Ardini F, Salis A, Damonte G, Rivaro P.
Combining voltammetric and mass spectrometric data to evaluate iron organic speciation in subsurfacecoastal seawater samples of the Ross sea (Antarctica).
Environ Sci Pollut Res Int. 2023 Feb;30(10):26718-26734. doi: 10.1007/s11356-022-23975-w.
Fiore M, Mosconi M, Bonì F, Parodi A, Salis A, Tasso B, Mastrangelo E, Millo E, Cossu F.
New Class of Benzodiazepinone Derivatives as Pro-Death Agents Targeting BIR Domains in Cancer Cells.
Molecules. 2023 Jan 3;28(1):446. doi: 10.3390/molecules28010446.
Baroni D, Scarano N, Ludovico A, Brandas C, Parodi A, Lunaccio D, Fossa P, Moran O, Cichero E, Millo E.
In Silico and In Vitro Evaluation of the Mechanism of Action of Three VX809-Based Hybrid Derivatives as Correctors of the F508delCFTR Protein.
Pharmaceuticals (Basel). 2023 Dec 8;16(12):1702. doi: 10.3390/ph16121702.
Scarano N, Di Palma F, Origlia N, Musumeci F, Schenone S, Spinelli S, Passalacqua M, Zocchi E, Sturla L, Cichero E, Cavalli A.
New Insights into the LANCL2-ABA Binding Mode towards the Evaluation of New LANCL Agonists.
Pharmaceutics.2023 Dec 12;15(12):2754. doi: 10.3390/pharmaceutics15122754.
Spinelli S, Guida L, Passalacqua M, Magnone M, Cossu V, Sambuceti G, Marini C, Sturla L, Zocchi E.
Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα.
Antioxidants (Basel). 2023 Aug 30;12(9):1692. doi: 10.3390/antiox12091692.
Spinelli S, Magnone M, Guida L, Sturla L, Zocchi E.
The ABA/LANCL Hormone/Receptor System in the Control of Glycemia, of Cardiomyocyte Energy Metabolism, and in Neuroprotection: A New Ally in the Treatment of Diabetes Mellitus?
Int J Mol Sci. 2023 Jan 7;24(2):1199. doi: 10.3390/ijms24021199.
Spinelli S, Cossu V, Passalacqua M, Hansen JB, Guida L, Magnone M, Sambuceti G, Marini C, Sturla L, Zocchi E.
The ABA/LANCL1/2 Hormone/Receptor System Controls Adipocyte Browning and Energy Expenditure.
Int J Mol Sci. 2023 Feb 9;24(4):3489. doi: 10.3390/ijms24043489.
Bruschi M, Angeletti A, Kajana X, Moroni G, Sinico RA, Fredi M, Vaglio A, Cavagna L, Pratesi F, Migliorini P, Locatelli F, Pazzola G, Pesce G, Bagnasco M, Manfredi A, Ramirez GA, Esposito P, Negrini S, Bui F, Trezzi B, Emmi G, Cavazzana I, Binda V, Fenaroli P, Pisani I, Montecucco C, Santoro D, Scolari F, Volpi S, Mosca M, Tincani A, Candiano G, Verrina E, Franceschini F, Ravelli A, Prunotto M, Meroni PL, Ghiggeri GM.
Evidence for charge-based mimicry in anti dsDNA antibody generation.
J Autoimmun. 2022 Oct;132:102900. doi: 10.1016/j.jaut.2022.102900.
Bruschi M, Kajana X, Petretto A, Bartolucci M, Pavanello M, Ghiggeri GM, Panfoli I, Candiano G.
Weighted Gene Co-Expression Network Analysis and Support Vector Machine Learning in the Proteomic Profiling of Cerebrospinal Fluid from Extraventricular Drainage in Child Medulloblastoma.
Metabolites. 2022 Aug 5;12(8):724. doi: 10.3390/metabo12080724.
Mishra S, Cosentino C, Tamta AK, Khan D, Srinivasan S, Ravi V, Abbotto E, Arathi BP, Kumar S, Jain A, Ramaian AS, Kizkekra SM, Rajagopal R, Rao S, Krishna S, Asirvatham-Jeyaraj N, Haggerty ER, Silberman DM, Kurland IJ, Veeranna RP, Jayavelu T, Bruzzone S, Mostoslavsky R, Sundaresan NR.
Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.
Nat Commun. 2022 Sep 15;13(1):5415. doi: 10.1038/s41467-022-32905-w.
Raffaghello L, Principi E, Baratto S, Panicucci C, Pintus S, Antonini F, Del Zotto G, Benzi A, Bruzzone S, Scudieri P, Minetti C, Gazzerro E, Bruno C.
P2X7 Receptor Antagonist Reduces Fibrosis and Inflammation in a Mouse Model of Alpha-Sarcoglycan Muscular Dystrophy.
Pharmaceuticals (Basel). 2022 Jan 13;15(1):89. doi: 10.3390/ph15010089.
Rutigliani M, Bozzo M, Barberis A, Greppi M, Anelli E, Castellaro L, Bonsignore A, Azzinnaro A, Pesce S, Filauro M, Rollandi GA, Castagnola P, Candiani S, Marcenaro E.
Case Report: A Peculiar Case of Inflammatory Colitis After SARS-CoV-2 Infection.
Front Immunol. 2022 Feb 9;13:849140. doi:10.3389/fimmu.2022.849140.
Bozzo M, Pasquale C, Cuccaro F, Ferrando S, Zekly A, Candiani S, Amaroli A.
Photobiomodulation Therapy through a Novel Flat-Top Hand-Piece Prototype Improves Tissue Regeneration in Amphioxus (Branchiostoma lanceolatum): Proposal of an Ethical Model for Preclinical Screening.
Photonics 2022, 9(7), 503. doi: 10.3390/photonics9070503.
Diab F, Khalil M, Lupidi G, Zbeeb H, Salis A, Damonte G, Bramucci M, Portincasa P, Vergani L.
Influence of Simulated In Vitro Gastrointestinal Digestion on the Phenolic Profile, Antioxidant, and Biological Activity of Thymbra spicata L. Extracts.
Antioxidants (Basel). 2022 Sep 9;11(9):1778. doi: 10.3390/antiox11091778.
Gatta E, Bazzurro V, Angeli E, Salis A, Damonte G, Cupello A, Robello M, Diaspro A.
Electrophysiological study of the effects of side products of RuBi- GABA uncaging on GABAA receptors in cerebellar granule cells.
Biomol Concepts. 2022 Jun 8;13(1):289-297. doi: 10.1515/bmc-2022-0022.
Adriano E, Salis A, Damonte G, Millo E, Balestrino M.
Effects of Delivering Guanidinoacetic Acid or Its Prodrug to the Neural Tissue: Possible Relevance for Creatine Transporter Deficiency.
Brain Sci. 2022 Jan 7;12(1):85. doi:10.3390/brainsci12010085.
Parodi A, Righetti G, Pesce E, Salis A, Tomati V, Pastorino C, Tasso B, Benvenuti M, Damonte G, Pedemonte N, Cichero E, Millo E.
Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays.
Pharmaceuticals (Basel). 2022 Feb 23;15(3):274. doi: 10.3390/ph15030274.
Magnone M, Spinelli S, Begani G, Guida L, Sturla L, Emionite L, Zocchi E.
Abscisic Acid Improves Insulin Action on Glycemia in Insulin-Deficient Mouse Models of Type 1 Diabetes.
Metabolites. 2022 Jun 6;12(6):523. doi: 10.3390/metabo12060523.
Spinelli S, Guida L, Vigliarolo T, Passalacqua M, Begani G, Magnone M, Sturla L, Benzi A, Ameri P, Lazzarini E, Bearzi C, Rizzi R, Zocchi E.
The ABA-LANCL1/2 Hormone-Receptors System Protects H9c2 Cardiomyocytes from Hypoxia-Induced Mitochondrial Injury via an AMPK- and NO-Mediated Mechanism.
Cells. 2022 Sep 15;11(18):2888. doi: 10.3390/cells11182888